BDBM493339 US10981917, Example 40::US10981917, Example 43

SMILES c1cc(c(c2c1n(cn2)CCC[C@@H]3[C@H](CCCN3)O)Cl)Cl

InChI Key InChIKey=VXCNMWNXDDMFSX-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 493339   

TargetRibose-phosphate pyrophosphokinase 1(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM493339(US10981917, Example 43 | US10981917, Example 40)
Affinity DataIC50: 100nMAssay Description:In order to confirm the biological activities of the compounds prepared in Examples, % inhibition or IC50 values of PRS enzyme (phosphoribosylpyropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2021
Entry Details
US Patent

TargetRibose-phosphate pyrophosphokinase 1(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM493339(US10981917, Example 43 | US10981917, Example 40)
Affinity DataIC50: 100nMAssay Description:In order to confirm the biological activities of the compounds prepared in Examples, % inhibition or IC50 values of PRS enzyme (phosphoribosylpyropho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2021
Entry Details
US Patent