BDBM493339 US10981917, Example 40::US10981917, Example 43

SMILES O[C@H]1CCCN[C@@H]1CCCn1cnc2c(Cl)c(Cl)ccc12

InChI Key InChIKey=VXCNMWNXDDMFSX-YPMHNXCESA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 493339   

TargetRibose-phosphate pyrophosphokinase 1(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM493339(US10981917, Example 40 | US10981917, Example 43)
Affinity DataIC50: <100nMAssay Description:In order to confirm the biological activities of the compounds prepared in Examples, % inhibition or IC50 values of PRS enzyme (phosphoribosylpyropho...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRibose-phosphate pyrophosphokinase 1(Homo sapiens (Human))
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM493339(US10981917, Example 40 | US10981917, Example 43)
Affinity DataIC50: <100nMAssay Description:In order to confirm the biological activities of the compounds prepared in Examples, % inhibition or IC50 values of PRS enzyme (phosphoribosylpyropho...More data for this Ligand-Target Pair
In DepthDetails US Patent