BDBM50002173 3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)butyl]-1H-indol-5-ol::3-[4-(4-phenyl-3,6-dihydropyridin-1(2H)-yl)butyl]-1H-indol-5-ol::CHEMBL431367::roxindole

SMILES: Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c3ccccc3)c2c1

InChI Key: InChIKey=HGEYJZMMUGWEOT-UHFFFAOYSA-N

Data: 27 KI  4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50002173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Rat)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.370	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		1.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1D adrenergic receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		1.35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		1.78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A adrenergic receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		2.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		2.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1B adrenergic receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		2.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		4.37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		4.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		5.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		6.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		6.61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor [16-465] (Rat)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		27.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		30.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1D (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Guinea pig)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1B) dopamine receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2C (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		468	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		2.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Rat)	BDBM50002173 (CHEMBL431367 | roxindole | 3-(4-(3,6-dihydro-4-phe...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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