BindingDB PrimarySearch

BDBM50013515 (+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester

SMILES: COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12

InChI Key: InChIKey=BLGXFZZNTVWLAY-SCYLSFHTSA-N

Data: 299 KI 17 IC50 8 Kd 3 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 327 hits for monomerid = 50013515
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-HT5B (RAT)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of [3H]prazosin binding to human Alpha-1A adrenergic receptor expressed in CHO cells				J Med Chem 38: 3681-716 (1995) Article DOI: 10.1021/jm00019a001 BindingDB Entry DOI: 10.7270/Q2SB46C4
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica Curated by PDSP K_i Database									Eur J Pharmacol 129: 49-55 (1986) BindingDB Entry DOI: 10.7270/Q27S7M8D
Janssen Pharmaceutica Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha1 (RABBIT)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Smith Kline & French Laboratories Curated by PDSP K_i Database									J Pharmacol Exp Ther 236: 90-6 (1986) BindingDB Entry DOI: 10.7270/Q2T72FXQ
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier, Centre de Recherches de Croissy Curated by PDSP K_i Database									Synapse 35: 79-95 (2000) Article DOI: 10.1002/(SICI)1098-2396(200002)35:2 BindingDB Entry DOI: 10.7270/Q2XK8D4N
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Mol Pharmacol 42: 180-5 (1992) BindingDB Entry DOI: 10.7270/Q2416VJ0
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U. 114 Curated by PDSP K_i Database									Nature 305: 140-2 (1983) Article DOI: 10.1038/305140a0 BindingDB Entry DOI: 10.7270/Q2S46QFX
INSERM U. 114 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Medical University of South Carolina Curated by PDSP K_i Database									Biochemistry 33: 4283-90 (1994) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2X928TX
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM U. 114 Curated by PDSP K_i Database									Nature 305: 140-2 (1983) Article DOI: 10.1038/305140a0 BindingDB Entry DOI: 10.7270/Q2S46QFX
INSERM U. 114 Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR2C (PIG)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-University Jena Curated by PDSP K_i Database									Br J Pharmacol 130: 692-8 (2000) Article DOI: 10.1038/sj.bjp.0703341 BindingDB Entry DOI: 10.7270/Q2M32T9Z
					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for 5-HT 2A in rat stomach fundus				J Med Chem 39: 2773-80 (1996) Article DOI: 10.1021/jm960062t BindingDB Entry DOI: 10.7270/Q2DZ09G0
Lilly Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C) (Homo sapiens (human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Eli Lilly and Company Curated by PDSP K_i Database									J Pharmacol Exp Ther 276: 720-7 (1996) BindingDB Entry DOI: 10.7270/Q29W0D1S
Eli Lilly and Company Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro binding affinity to Dopamine receptors of rat striatal membranes by [3H]spiroperidol displacement.				J Med Chem 29: 1394-8 (1986) Article DOI: 10.1021/jm00158a013
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by PDSP K_i Database									J Pharmacol Exp Ther 241: 1092-8 (1987) BindingDB Entry DOI: 10.7270/Q2F18X7B
University of California Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adrenergic alpha1B (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									J Pharmacol Exp Ther 302: 58-65 (2002) BindingDB Entry DOI: 10.7270/Q2PG1Q9R
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Dopamine receptor (Rattus norvegicus (Rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Tested for binding affinity against dopamine receptor D3 expressed in Sf9 cells.				J Med Chem 36: 1499-500 (1993) Article DOI: 10.1021/jm00062a025 BindingDB Entry DOI: 10.7270/Q2F47PRT
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Dopamine receptor (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank PubMed	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-Hydroxytryptamine receptor 7 (5-HT7) (Homo sapiens (human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									J Biol Chem 268: 23422-6 (1993) Article DOI: 10.1016/j.bioorg.2015.04.004 BindingDB Entry DOI: 10.7270/Q28G8J68
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									J Pharmacol Exp Ther 302: 58-65 (2002) BindingDB Entry DOI: 10.7270/Q2PG1Q9R
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	3.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by PDSP K_i Database									Mol Pharmacol 42: 180-5 (1992) BindingDB Entry DOI: 10.7270/Q2416VJ0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 621-9 BindingDB Entry DOI: 10.7270/Q2NV9GSN
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Dopamine receptor (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier, Centre de Recherches de Croissy Curated by PDSP K_i Database									Synapse 35: 79-95 (2000) Article DOI: 10.1002/(SICI)1098-2396(200002)35:2 BindingDB Entry DOI: 10.7270/Q2XK8D4N
					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	4.47E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-HT1 (Homo sapiens (human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Heidelberg Curated by PDSP K_i Database									EMBO J 10: 4017-23 (1991) BindingDB Entry DOI: 10.7270/Q28K77K4
University of Heidelberg Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by PDSP K_i Database									Br J Pharmacol 114: 400-4 (1995) Article DOI: 10.1016/j.bioorg.2014.11.008 BindingDB Entry DOI: 10.7270/Q2SN07F1
					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	7.54E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by PDSP K_i Database									J Pharmacol Exp Ther 260: 614-26 (1992) BindingDB Entry DOI: 10.7270/Q2SJ1J3M
University of Texas Curated by PDSP K_i Database					More data for this Ligand-Target Pair
adrenergic Alpha2 (RAT)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	7.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984) BindingDB Entry DOI: 10.7270/Q25B00Z5
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by PDSP K_i Database									J Pharmacol Exp Ther 260: 614-26 (1992) BindingDB Entry DOI: 10.7270/Q2SJ1J3M
University of Texas Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 621-9 BindingDB Entry DOI: 10.7270/Q2NV9GSN
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Calcium channel (RAT)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Marion Merrell Dow Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 253: 461-5 (1990) BindingDB Entry DOI: 10.7270/Q2SF2TPW
Marion Merrell Dow Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C) (Homo sapiens (human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 621-9 BindingDB Entry DOI: 10.7270/Q2NV9GSN
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Neuropharmacology 36: 621-9 BindingDB Entry DOI: 10.7270/Q2NV9GSN
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									Br J Pharmacol 115: 622-8 (1995) BindingDB Entry DOI: 10.7270/Q2BR8QP0
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									Br J Pharmacol 115: 622-8 (1995) BindingDB Entry DOI: 10.7270/Q2BR8QP0
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C) (Homo sapiens (human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									Br J Pharmacol 115: 622-8 (1995) BindingDB Entry DOI: 10.7270/Q2BR8QP0
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-Hydroxytryptamine receptor 2C (5-HT2C) (Homo sapiens (human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									Br J Pharmacol 115: 622-8 (1995) BindingDB Entry DOI: 10.7270/Q2BR8QP0
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Discovery Research Curated by PDSP K_i Database									Br J Pharmacol 115: 622-8 (1995) BindingDB Entry DOI: 10.7270/Q2BR8QP0
Syntex Discovery Research Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-HT5 (MOUSE)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Max-Planck-Institut Curated by PDSP K_i Database									FEBS Lett 377: 451-6 (1995) BindingDB Entry DOI: 10.7270/Q2M9076W
Max-Planck-Institut Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (5HT2C) (Mus musculus (Mouse))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity analysed towards 5-HT 2C in rat stomach fundus				J Med Chem 39: 2773-80 (1996) Article DOI: 10.1021/jm960062t BindingDB Entry DOI: 10.7270/Q2DZ09G0
Lilly Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (5HT1B) (Mus musculus (Mouse))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta Curated by PDSP K_i Database									Neuropharmacology 33: 275-317 BindingDB Entry DOI: 10.7270/Q2M043X2
University of Alberta Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Imidazoline I1 (RAT)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bonn Curated by PDSP K_i Database									J Pharmacol Exp Ther 285: 170-7 (1998) BindingDB Entry DOI: 10.7270/Q27H1H4B
University of Bonn Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-HT3A Serotonin Receptor (Mus musculus (house mouse))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
HTR2C (PIG)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-University Jena Curated by PDSP K_i Database									Br J Pharmacol 130: 692-8 (2000) Article DOI: 10.1038/sj.bjp.0703341 BindingDB Entry DOI: 10.7270/Q2M32T9Z
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SRI International Curated by PDSP K_i Database									NIDA Res Monogr 178: 440-66 (1998) BindingDB Entry DOI: 10.7270/Q23J3BH2
SRI International Curated by PDSP K_i Database					More data for this Ligand-Target Pair
OPIATE Sigma (RAT)	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 81: 4983-7 (1984) BindingDB Entry DOI: 10.7270/Q2JM284N
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
phosphatase Cdc25 (Homo sapiens (Human))	BDBM50013515 ((+)-yohimbine \| (16alpha,17alpha)-17-hydroxyyohimb...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Max Planck Institute of Molecular Physiology Curated by ChEMBL					Assay Description Inhibition of His-tagged Cdc25A expressed in the Escherichia coli BL21(DE3) using p-nitrophenyl phosphate as substrate for 80 mins by spectrophotomet...				J Med Chem 55: 5989-6001 (2012) Article DOI: 10.1021/jm300288g BindingDB Entry DOI: 10.7270/Q2J38TPJ
					More data for this Ligand-Target Pair

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