BDBM50015448 CHEMBL3265032

SMILES: C1CN(CCO1)c1ccc(Nc2nc(cn3ccnc23)-c2ccc3cn[nH]c3c2)cc1

InChI Key: InChIKey=XSMSNFMDVXXHGJ-UHFFFAOYSA-N

Data: 16 IC50  12 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 37 hits for monomerid = 50015448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	26	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	367	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	453	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Mast/stem cell growth factor receptor Kit (Mouse)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	445	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	327	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	125	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Rat)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	878	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase ROS (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	857	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	178	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	801	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	303	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	569	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Casein kinase II subunit alpha 3 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	604	n/a	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 6 (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	842	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM50015448 (CHEMBL3265032) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair