BDBM50022086 6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phenyl)piperidin-1-yl)benzyl) imidazo(1,2-a)pyridine-3-carboxamide::CHEMBL3298910::Q203::Telacebec

SMILES CCc1c(n2cc(ccc2n1)Cl)C(=O)NCc3ccc(cc3)N4CCC(CC4)c5ccc(cc5)OC(F)(F)F

InChI Key InChIKey=OJICYBSWSZGRFB-UHFFFAOYSA-N

Data  5 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50022086   

TargetCytochrome P450 2D6(Human)
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50022086(CHEMBL3298910 | Q203 | 6-chloro-2-ethyl-N-(4-(4-(4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant CYP2D6 (unknown origin) by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50022086(CHEMBL3298910 | Q203 | 6-chloro-2-ethyl-N-(4-(4-(4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant CYP1A2 (unknown origin) by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50022086(CHEMBL3298910 | Q203 | 6-chloro-2-ethyl-N-(4-(4-(4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50022086(CHEMBL3298910 | Q203 | 6-chloro-2-ethyl-N-(4-(4-(4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50022086(CHEMBL3298910 | Q203 | 6-chloro-2-ethyl-N-(4-(4-(4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2015
Entry Details Article
PubMed