BDBM50022086 6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phenyl)piperidin-1-yl)benzyl) imidazo(1,2-a)pyridine-3-carboxamide::CHEMBL3298910::Q203::Telacebec

SMILES CCc1nc2ccc(Cl)cn2c1C(=O)NCc1ccc(cc1)N1CCC(CC1)c1ccc(OC(F)(F)F)cc1

InChI Key InChIKey=OJICYBSWSZGRFB-UHFFFAOYSA-N

Data  5 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50022086   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50022086(6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin) by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50022086(6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant CYP2D6 (unknown origin) by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50022086(6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin) by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50022086(6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin) by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50022086(6-chloro-2-ethyl-N-(4-(4-(4-(trifluoromethoxy)phen...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant CYP1A2 (unknown origin) by LC/MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed