BDBM50029885 (3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7,7-diphenyl-octahydro-isoindol-4-one::2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7,7-diphenyl-octahydro-isoindol-4-one::CHEMBL131171::RP 67,580::RP-67580
SMILES COc1ccccc1CC(=N)N1C[C@H]2[C@@H](C1)C(CCC2=O)(c1ccccc1)c1ccccc1
InChI Key InChIKey=VWBOQFANCXZMAU-LOSJGSFVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50029885
Affinity DataKi: 4.20nMAssay Description:Tested for binding affinity towards Tachykinin receptor 1 by using [3H]-SP binding assay in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70nMAssay Description:Inhibitory activity of the compound against Tachykinin receptor 1 in mouse brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against Tachykinin receptor 1 in human IM-9 cells using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]-SP binding assay on human IM9 lymphoblasts cultured cell line.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]-SP binding assay on rat brain membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibitory activity of the compound against Tachykinin receptor 1 in guinea pig brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 4.16E+3nMAssay Description:Inhibition of [3H]-SP binding in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibitory activity of the compound against Tachykinin receptor 1 in rat brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair