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Found 10 Enz. Inhib. hit(s) with Target = 'Substance-P receptor' and Ligand = 'BDBM50029885'
TargetSubstance-P receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50029885((3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7...)
Affinity DataKi:  4.20nMAssay Description:Tested for binding affinity towards Tachykinin receptor 1 by using [3H]-SP binding assay in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50029885((3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7...)
Affinity DataKi:  8.29nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSubstance-P receptor(GUINEA PIG)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50029885((3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7...)
Affinity DataKi:  36nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSubstance-P receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50029885((3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7...)
Affinity DataIC50:  6.70nMAssay Description:Inhibitory activity of the compound against Tachykinin receptor 1 in rat brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50029885((3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7...)
Affinity DataIC50:  8nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]-SP binding assay on rat brain membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Mus musculus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029885((3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7...)
Affinity DataIC50:  8.70nMAssay Description:Inhibitory activity of the compound against Tachykinin receptor 1 in mouse brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029885((3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7...)
Affinity DataIC50:  30nMAssay Description:Inhibitory activity against Tachykinin receptor 1 in human IM-9 cells using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(GUINEA PIG)
Hoechst Marion Roussel

Curated by PDSP Ki Database
LigandPNGBDBM50029885((3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7...)
Affinity DataIC50:  32nMAssay Description:Inhibitory activity of the compound against Tachykinin receptor 1 in guinea pig brain using [125I]-labeled Boltan-Hunter substance P as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50029885((3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7...)
Affinity DataIC50:  49nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]-SP binding assay on human IM9 lymphoblasts cultured cell line.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSubstance-P receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50029885((3aR,7aR)-2-[1-Imino-2-(2-methoxy-phenyl)-ethyl]-7...)
Affinity DataIC50:  4.16E+3nMAssay Description:Inhibition of [3H]-SP binding in rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed