BDBM50058225 CHEMBL45244::N-((4-(2-cyanophenyl)piperazin-1-yl)methyl)-3-methylbenzamide::N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-methyl-benzamide::PD-168077

SMILES: Cc1cccc(c1)C(=O)NCN1CCN(CC1)c1ccccc1C#N

InChI Key: InChIKey=DNULYRGWTFLJQL-UHFFFAOYSA-N

Data: 21 KI  1 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 29 hits for monomerid = 50058225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.30	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.90	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.30	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		8.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		8.71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		17.0	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Bovine)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(4) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor [16-465] (Rat)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		168	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine receptor A2b (Rat)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 1A (Mouse)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		385	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		2.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		3.74E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		3.74E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		4.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Bovine)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		6.48E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(1A) dopamine receptor (Bovine)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Bovine)	BDBM50058225 (N-[4-(2-Cyano-phenyl)-piperazin-1-ylmethyl]-3-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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