BDBM50067928 CHEMBL544623::N-{1-[3-(2-Methyl-quinolin-8-yloxymethyl)-2,4-bis-(2-pyridin-4-yl-vinyl)-phenyl]-1H-pyrrol-2-ylmethyl}-3-[6-(2-pyridin-4-yl-vinyl)-pyridin-3-yl]-acrylamide

SMILES Cc1ccc2cccc(OCc3c(\C=C\c4ccncc4)ccc(c3\C=C\c3ccncc3)-n3cccc3CNC(=O)\C=C\c3ccc(\C=C\c4ccncc4)nc3)c2n1

InChI Key InChIKey=GILVQLPJVQETDU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50067928   

TargetB2 bradykinin receptor(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067928(N-{1-[3-(2-Methyl-quinolin-8-yloxymethyl)-2,4-bis-...)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of the specific binding of [3H]BK to human recombinant Bradykinin receptor B2 expressed in CHO cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetB2 bradykinin receptor(Guinea pig)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50067928(N-{1-[3-(2-Methyl-quinolin-8-yloxymethyl)-2,4-bis-...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of the specific binding of [3H]BK to Bradykinin receptor B2 in guinea pig ileum membrane preparationsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed