BDBM50079401 CHEMBL62381::Sodium butyrate::Sodium; butyrate::butanoate::butyrate
SMILES CCCC([O-])=O
InChI Key InChIKey=FERIUCNNQQJTOY-UHFFFAOYSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50079401
Affinity DataKi: 2.69E+4nMAssay Description:Inhibition of Candida albicans Nce103More data for this Ligand-Target Pair
TargetCarbonic anhydrase [110-330](Flaveria bidentis (Coastal plain yellowtops))
Istituto Di Biostrutture E Bioimmagini-Cnr
Istituto Di Biostrutture E Bioimmagini-Cnr
Affinity DataKi: 8.23E+4nM ΔG°: -5.47kcal/molepH: 8.3 T: 2°CAssay Description:Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C.More data for this Ligand-Target Pair
Affinity DataKi: 3.65E+5nMAssay Description:Inhibition of HDAC in human Hela cells nuclear extracts by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.11E+5nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.03E+6nMAssay Description:Inhibition of human carbonic anhydrase2More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human recombinant His-tagged HDAC1 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant full-length His-tagged HDAC2 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based ana...More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant His-tagged HDAC3 expressed in baculovirus expression system incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+5nMAssay Description:Inhibition of HDAC in human Hela cells nuclear extracts by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibitory activity against partially purified histone deacetylase of human leukemia K562 cells.More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Chengdu University Of Traditional Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant His-tagged HDAC8 expressed in Escherichia coli incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of LPS-induced tissue factor activity in HUVEC preincubated for 4 hrs assessed after 4 hrs of LPS challenge by one stage clotting assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.01E+4nMAssay Description:Agonist activity at GPR41 (unknown origin) by Fluo-4 AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of TNF-alpha-induced tissue factor activity in HUVEC preincubated for 4 hrs assessed after 4 hrs of TNFalpha challenge by one stage clotti...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 50079401
ITC DataΔG°: -1.50kcal/mole −TΔS°: 1.03kcal/mole ΔH°: -2.53kcal/mole logk: 12.5
pH: 6.9 T: 25.00°C
pH: 6.9 T: 25.00°C