BDBM50112086 3-({2-[(4-Carbamimidoyl-phenylamino)-methyl]-1-methyl-1H-benzoimidazole-5-carbonyl}-pyridin-2-yl-amino)-propionic acid::CHEMBL48361::DABIGATRAN

SMILES: [H]/N=C(c1ccc(cc1)NCc2nc3cc(ccc3n2C)C(=O)N(CCC(=O)O)c4ccccn4)/N

InChI Key: InChIKey=YBSJFWOBGCMAKL-UHFFFAOYSA-N

Data: 15 KI  21 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 50112086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosyldihydronicotinamide dehydrogenase [quinone] (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosyldihydronicotinamide dehydrogenase [quinone] (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 2 (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
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Multidrug and toxin extrusion protein 1 (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 2 (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor XII (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
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Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prothrombin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Trypsin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1/Trypsin-2 (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		50.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease hepsin (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		835	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Plasminogen (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		3.76E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor X (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Vitamin K-dependent protein C (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		2.09E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tissue-type plasminogen activator (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		4.54E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosyldihydronicotinamide dehydrogenase [quinone] (Human)	BDBM50112086 (CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...) Show SMILES Show InChI	GoogleScholar	UniChem		6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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