BDBM50121977 2-(3,4-Dimethoxy-phenyl)-5-[2-(3,4-dimethoxy-phenyl)-ethylamino]-2-isopropyl-pentanenitrile::CHEMBL1298::Norverapamil (6%)

SMILES: COc1ccc(CCNCCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC

InChI Key: InChIKey=UPKQNCPKPOLASS-UHFFFAOYSA-N

Data: 4 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50121977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent translocase ABCB1 (Human)	BDBM50121977 (Norverapamil (6%) | 2-(3,4-Dimethoxy-phenyl)-5-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50121977 (Norverapamil (6%) | 2-(3,4-Dimethoxy-phenyl)-5-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM50121977 (Norverapamil (6%) | 2-(3,4-Dimethoxy-phenyl)-5-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50121977 (Norverapamil (6%) | 2-(3,4-Dimethoxy-phenyl)-5-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A5 (Human)	BDBM50121977 (Norverapamil (6%) | 2-(3,4-Dimethoxy-phenyl)-5-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		4.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50121977 (Norverapamil (6%) | 2-(3,4-Dimethoxy-phenyl)-5-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		5.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Human)	BDBM50121977 (Norverapamil (6%) | 2-(3,4-Dimethoxy-phenyl)-5-[2-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair