BDBM50126761 (S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-YL) PROPRIONIC ACID::2-Amino-3-(5-tert-butyl-3-hydroxy-isothiazol-4-yl)-propionic acid::CHEMBL29024

SMILES CC(C)(C)c1s[nH]c(=O)c1C[C@H](N)C(O)=O

InChI Key InChIKey=FHWOAQCPEFTDOQ-LURJTMIESA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50126761   

TargetGlutamate receptor(Xenopus laevis)
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50126761((S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-...)
Affinity DataEC50:  4.90E+3nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing heteromeric Ionotropic glutamate receptor ionotropic kainate 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50126761((S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-...)
Affinity DataEC50:  3.20E+4nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 3 (GluR3o)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetGlutamate receptor ionotropic, kainate 5(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50126761((S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-...)
Affinity DataEC50:  100nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric kainate receptor (GluR5)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126761((S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-...)
Affinity DataEC50:  5.20E+3nMAssay Description:Agonist activity at GluA1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126761((S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-...)
Affinity DataEC50:  5.20E+3nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 1 (GluR1o)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50126761((S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at GluK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Homo sapiens (Human))
The Danish University Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50126761((S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-...)
Affinity DataEC50:  2.00E+4nMAssay Description:Electrophysiological data on Xenopus oocytes, expressing homomeric Ionotropic glutamate receptor AMPA 3 (GluR4o)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed