BDBM50151363 4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiazol-2-ylamine::4-(3-chlorophenyl)-5-(1,5-naphthyridin-2-yl)thiazol-2-amine::CHEMBL365663

SMILES: Nc1nc(c(s1)-c1ccc2ncccc2n1)-c1cccc(Cl)c1

InChI Key: InChIKey=JVXFJMXCRSAZFH-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50151363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase (Cryptosporidium parvum (strain Iowa II))	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cgd5_820 protein (Cryptosporidium parvum)	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cell division control protein 28, putative (Cryptosporidium parvum (strain Iowa II))	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands (Cryptosporidium parvum (strain Iowa II))	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cgd2_1060 protein (Cryptosporidium parvum)	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands (Cryptosporidium parvum (strain Iowa II))	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50151363 (4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiaz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair