BDBM50177053 9-Dimethylamino-3-(4-ethyl-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::9-dimethylamino-3-(4-ethylphenyl)-3H-5-thia-1,3,6-triazafluoren-4-one::CHEMBL385336
SMILES CCc1ccc(cc1)-n1cnc2c(sc3nccc(N(C)C)c23)c1=O
InChI Key InChIKey=VCUKKMIXURRDKL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50177053
Affinity DataKi: 5nMAssay Description:Displacement of [3H]R214127 from mGluR1 in rat cerebellum membranesMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: 194nMAssay Description:Displacement of [3H]MPEP from rat cortex mGluR5More data for this Ligand-Target Pair
Affinity DataIC50: 442nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human mGluR4 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at mGlu1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human mGluR2 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 442nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.33E+3nMAssay Description:Antagonist activity at rat mGluR5 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat mGluR1 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of rat mGluR1More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human mGluR7 expressed in 1321N1 cellsMore data for this Ligand-Target Pair