BindingDB PrimarySearch

BDBM50184359 (3S,6S,9R,12S,15S,23S)-15-((S)-2-acetylamino-hexanoylamino)-9-benzyl-6-(3-guanidino-propyl)-12-(3H-imidazol-4-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18hexaaza-cyclotricosane-23-carboxylic acid amide::Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2::Ac-Nle-c[Asp-His-DPhe-Arg-Trp-Lys]-NH2::CHEMBL430239::MT-II::ebi_340792

SMILES: CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CC(=O)NCCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC1=O)C(N)=O

InChI Key: InChIKey=JDKLPDJLXHXHNV-UHFFFAOYSA-N

Data: 27 IC50 39 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 66 hits for monomerid = 50184359
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Melanocortin receptor 4 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 3 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.190	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Melanocortin receptor 5 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 5 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.0400	n/a	n/a	n/a	n/a
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Melanocortin receptor 3 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.240	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Mouse)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.0870	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 4 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	2.10	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 3 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	5.10	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 3 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
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Melanocortin receptor 3 (Mouse)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.160	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Mouse)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.160	n/a	n/a	n/a	n/a
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Melanocyte-stimulating hormone receptor (Mouse)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.0200	n/a	n/a	n/a	n/a
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Melanocortin receptor 3 (Mouse)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.160	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Mouse)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.160	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Mouse)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.0870	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocyte-stimulating hormone receptor (Mouse)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.0200	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
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Melanocortin receptor 3 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 3 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocortin receptor 4 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	2.90	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 3 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	2.90	n/a	n/a	n/a	n/a
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Melanocortin receptor 5 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Melanocortin receptor 4 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 5 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 3 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 3 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 3 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 4 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 4 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocortin receptor 5 (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
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Melanocyte-stimulating hormone receptor (Human)	BDBM50184359 (MT-II \| CHEMBL430239 \| Ac-Nle-c[Asp-His-DPhe-Arg-T...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
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