BDBM50184872 4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-yl)-N-(tetrahydro-2H-pyran-4-yl)benzamide::4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-yl}-N-(tetrahydro-2H-pyran-4-yl)benzamide::CHEMBL202887::GW-788388

SMILES: O=C(NC1CCOCC1)c1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1

InChI Key: InChIKey=SAGZIBJAQGBRQA-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50184872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Human)	BDBM50184872 (4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50184872 (4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50184872 (4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transforming growth factor beta-1 proprotein (Human)	BDBM50184872 (4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	446	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50184872 (4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Human)	BDBM50184872 (4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair