BDBM50188913 CHEMBL213618::N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-5-(2-(methylamino)pyrimidin-4-yl)thiophene-2-carboxamide::N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE

SMILES: CNc1nccc(n1)-c1ccc(s1)C(=O)N[C@H](CN)Cc1ccc(Cl)cc1Cl

InChI Key: InChIKey=HHOVRZGUSBMKKU-UHFFFAOYSA-N

Data: 13 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50188913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-gamma serine/threonine-protein kinase (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
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cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C alpha type (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
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Calcium/calmodulin-dependent protein kinase type II subunit alpha (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
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RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-gamma serine/threonine-protein kinase (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-beta serine/threonine-protein kinase (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 3 (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM50188913 (N-((S)-1-amino-3-(2,4-dichlorophenyl)propan-2-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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