BDBM50214432 CHEMBL387924::octanedioic acid hydroxyamide [4-(3-nitro-phenyl)thiazol-2-yl]amide

SMILES ONC(=O)CCCCCCC(=O)Nc1nc(cs1)-c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=LJFNWCGSOPRFNA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50214432   

TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214432(CHEMBL387924 | octanedioic acid hydroxyamide [4-(3...)
Affinity DataIC50:  113nMAssay Description:Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214432(CHEMBL387924 | octanedioic acid hydroxyamide [4-(3...)
Affinity DataIC50:  4.09E+3nMAssay Description:Inhibition of His-tagged HDAC8 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214432(CHEMBL387924 | octanedioic acid hydroxyamide [4-(3...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214432(CHEMBL387924 | octanedioic acid hydroxyamide [4-(3...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214432(CHEMBL387924 | octanedioic acid hydroxyamide [4-(3...)
Affinity DataIC50:  11.1nMAssay Description:Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed