BDBM50224760 2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylcarbamoyl-beta-D-ribofuranosyl)adenine::CHEMBL254064

SMILES CNC(=O)OC[C@H]1O[C@@H](n2cnc3c(NC4CCCC4)nc(Cl)nc23)[C@](C)(O)[C@@H]1O

InChI Key InChIKey=IQPCHXGNQWZETD-UOYMAUKRSA-N

Data  6 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50224760   

TargetAdenosine receptor A1(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224760(2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylca...)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in pig cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224760(2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylca...)
Affinity DataKi:  156nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in bovine cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224760(2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylca...)
Affinity DataKi:  1.12E+3nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224760(2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylca...)
Affinity DataKi:  8.35E+3nMAssay Description:Agonist activity at human recombinant adenosine A2B receptor expressed in CHO cells assessed as activation of adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224760(2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylca...)
Affinity DataKi:  1.04E+4nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50224760(2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylca...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(GUINEA PIG)
Universit£

Curated by ChEMBL
LigandPNGBDBM50224760(2-chloro-N6-cyclopentyl-9H-(2-C-methyl-5-Nmethylca...)
Affinity DataEC50:  165nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed