BDBM50232263 (R)-N-((4-(2,4-dimethoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)(1H-indol-3-yl)methyl)benzamide::CHEMBL399651

SMILES COc1ccc(Cn2c(CCc3ccccc3)nnc2[C@H](NC(=O)c2ccccc2)c2c[nH]c3ccccc23)c(OC)c1

InChI Key InChIKey=AJMNYVOTXIKAAT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232263   

TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50232263((R)-N-((4-(2,4-dimethoxybenzyl)-5-phenethyl-4H-1,2...)
Affinity DataIC50: 11.8nMAssay Description:Displacement of 125I]-His9-ghrelin from human GHSR1a expressed in LLCPK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50232263((R)-N-((4-(2,4-dimethoxybenzyl)-5-phenethyl-4H-1,2...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at GHSR1a expressed in CHO cells assessed as accumulation of intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed