BDBM50248034 2-{[1-(7-Chloro-quinolin-4-yl)-5-(2,6-dimethoxy-phenyl)-1H-pyrazole-3-carbonyl]-amino}-adamantane-2-carboxylic acid::CHEMBL506981::SR 48692

SMILES: COc1cccc(c1c2cc(nn2c3ccnc4c3ccc(c4)Cl)C(=O)NC5(C6CC7CC(C6)CC5C7)C(=O)O)OC

InChI Key: InChIKey=DYLJVOXRWLXDIG-UHFFFAOYSA-N

Data: 6 KI  4 IC50  1 Kd  2 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50248034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurotensin receptor type 1 (Rat)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
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Neurotensin receptor type 1 (Human)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.990	n/a	n/a	n/a	n/a	n/a	n/a
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Neurotensin receptor type 1 (Human)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a
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Sortilin (Human)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	238	n/a	n/a	n/a	n/a	n/a	n/a
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Neurotensin receptor type 1 (Human)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a
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Neurotensin receptor type 2 (Rat)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
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Neurotensin receptor type 1 (Human)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
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Neurotensin (Guinea pig)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		0.990	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neurotensin (Guinea pig)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neurotensin receptor type 1 (Rat)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neurotensin (Guinea pig)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neurotensin receptor type 2 (Rat)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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5'-nucleotidase (Rat)	BDBM50248034 (CHEMBL506981 | SR 48692 | 2-{[1-(7-Chloro-quinolin...) Show SMILES Show InChI	GoogleScholar	UniChem		124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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