BDBM50295553 4-(4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)but-3-yn-1-ol::4-[4-(4-Fluoro-phenyl)-1-(3-phenyl-propyl)-5-pyridin-4-yl-1H-imidazol-2-yl]-but-3-yn-1-ol::CHEMBL190333::RWJ-67657::US11273153, Compound RWJ67657

SMILES: OCCC#Cc1nc(c(-c2ccncc2)n1CCCc1ccccc1)-c1ccc(F)cc1

InChI Key: InChIKey=QSUSKMBNZQHHPA-UHFFFAOYSA-N

Data: 6 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50295553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM50295553 (4-[4-(4-Fluoro-phenyl)-1-(3-phenyl-propyl)-5-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50295553 (4-[4-(4-Fluoro-phenyl)-1-(3-phenyl-propyl)-5-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase (Toxoplasma gondii)	BDBM50295553 (4-[4-(4-Fluoro-phenyl)-1-(3-phenyl-propyl)-5-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50295553 (4-[4-(4-Fluoro-phenyl)-1-(3-phenyl-propyl)-5-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50295553 (4-[4-(4-Fluoro-phenyl)-1-(3-phenyl-propyl)-5-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50295553 (4-[4-(4-Fluoro-phenyl)-1-(3-phenyl-propyl)-5-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50295553 (4-[4-(4-Fluoro-phenyl)-1-(3-phenyl-propyl)-5-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50295553 (4-[4-(4-Fluoro-phenyl)-1-(3-phenyl-propyl)-5-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Human)	BDBM50295553 (4-[4-(4-Fluoro-phenyl)-1-(3-phenyl-propyl)-5-pyrid...) Show SMILES Show InChI	GoogleScholar	UniChem		210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair