BDBM50337128 2-((4-(4-hydroxypiperidin-1-yl)-2-methoxyphenyl)amino-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one::CHEMBL1673040::US9266890, IV-7

SMILES: COc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(C)c2n1)N1CCC(O)CC1

InChI Key: InChIKey=YSFFGUHMDPYPAW-UHFFFAOYSA-N

Data: 3 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50337128   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 7 (Human)	BDBM50337128 (US9266890, IV-7 | 2-((4-(4-hydroxypiperidin-1-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase DCLK1 (Human)	BDBM50337128 (US9266890, IV-7 | 2-((4-(4-hydroxypiperidin-1-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
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Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM50337128 (US9266890, IV-7 | 2-((4-(4-hydroxypiperidin-1-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Leucine-rich repeat serine/threonine-protein kinase 2 (Human)	BDBM50337128 (US9266890, IV-7 | 2-((4-(4-hydroxypiperidin-1-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 7 (Human)	BDBM50337128 (US9266890, IV-7 | 2-((4-(4-hydroxypiperidin-1-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 7 (Human)	BDBM50337128 (US9266890, IV-7 | 2-((4-(4-hydroxypiperidin-1-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	297	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 7 (Human)	BDBM50337128 (US9266890, IV-7 | 2-((4-(4-hydroxypiperidin-1-yl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair