BindingDB PrimarySearch

BDBM50013515 (+)-yohimbine::(16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester::17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester::CHEMBL15245::CORYNANTHINE::Johimbin::Quebrachin::RAUWOLSCINE::YOHIMBINE CHLORIDE::Yohimbin::Yohimbine::aphrodine::cid_8969::corynine::methyl 17alpha-hydroxyyohimban-16alpha-carboxylate::quebrachine::yohimbic acid methyl ester

SMILES: COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12

InChI Key: InChIKey=BLGXFZZNTVWLAY-UHFFFAOYSA-N

Data: 306 KI 18 IC50 8 Kd 3 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 341 hits for monomerid = 50013515
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a
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POsterior Segregation (Caenorhabditis elegans)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.54E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent noradrenaline transporter (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Rat)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	165	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor [16-465] (Rat)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	8.5	n/a	n/a	n/a	n/a
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DNA topoisomerase 1 (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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M-phase inducer phosphatase 1 (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.98E+5	n/a	n/a	n/a	n/a	5.0	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.95E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	5.0	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	5.40E+6	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	5.40E+6	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 1/2/3 subunit alpha (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rat)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (OK)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (North American opossum)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (North American opossum)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-2 adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (North American opossum)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.0800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (North American opossum)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (OK)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (OK)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (North American opossum)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (North American opossum)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (OK)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (North American opossum)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Pig)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2C adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2A adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-2B adrenergic receptor (Human)	BDBM50013515 (yohimbic acid methyl ester \| 17alpha-hydroxyyohimb...) Show SMILES Show InChI	GoogleScholar	UniChem	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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