BDBM50375664 CHEMBL404939::US9422231, IMDNQ1

SMILES ClC1=C(N2C(=O)CCC2=O)C(=O)c2ccccc2C1=O

InChI Key InChIKey=GYQSWJNGTWVFOL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50375664   

TargetTubulin alpha chain(Trypanosoma cruzi)
Howard University

US Patent
LigandPNGBDBM50375664(CHEMBL404939 | US9422231, IMDNQ1)
Affinity DataIC50:  6.00E+3nMpH: 6.9 T: 2°CAssay Description:Tubulin assembly assays were conducted to assess tubulin polymerization inhibition. The assays were conducted in a 96-well microplate. Assembly react...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375664(CHEMBL404939 | US9422231, IMDNQ1)
Affinity DataIC50:  380nMAssay Description:Inhibition of MEK1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375664(CHEMBL404939 | US9422231, IMDNQ1)
Affinity DataIC50:  8.29E+4nMAssay Description:Inhibition of ERK1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375664(CHEMBL404939 | US9422231, IMDNQ1)
Affinity DataIC50:  50nMAssay Description:Inhibition of Tpl2 kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375664(CHEMBL404939 | US9422231, IMDNQ1)
Affinity DataIC50:  3.45E+4nMAssay Description:Inhibition of Raf1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed