BDBM50375664 CHEMBL404939::US9422231, IMDNQ1
SMILES ClC1=C(N2C(=O)CCC2=O)C(=O)c2ccccc2C1=O
InChI Key InChIKey=GYQSWJNGTWVFOL-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50375664
Affinity DataIC50: 6.00E+3nMpH: 6.9 T: 2°CAssay Description:Tubulin assembly assays were conducted to assess tubulin polymerization inhibition. The assays were conducted in a 96-well microplate. Assembly react...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 380nMAssay Description:Inhibition of MEK1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.29E+4nMAssay Description:Inhibition of ERK1Checked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Tpl2 kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 3.45E+4nMAssay Description:Inhibition of Raf1Checked by AuthorMore data for this Ligand-Target Pair