BDBM50381730 CHEMBL2023244

SMILES C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=Cc5c(C[C@]34C)cnn5-c3ccc(F)cc3)[C@@H]1CC[C@]2(O)C(=O)COc1ccc2ccccc2c1

InChI Key InChIKey=OUOOTSFAUFNOLK-FWTLZLCQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50381730   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50381730(CHEMBL2023244)
Affinity DataIC50:  29.2nMAssay Description:Transactivation activity at glucocorticoid receptor in human HepG2 cells assessed as induction of tyrosineaminotransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50381730(CHEMBL2023244)
Affinity DataIC50:  1.06nMAssay Description:Transrepression activity at glucocorticoid receptor in human H292 cells assessed as inhibition of TNF-induced IL8 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50381730(CHEMBL2023244)
Affinity DataIC50:  58nMAssay Description:Transactivation activity at glucocorticoid receptor in rat H4II-E cells assessed as induction of tyrosineaminotransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed