BDBM50388781 CHEMBL2062585

SMILES CC(=O)Nc1ccc2n(CCC(O)=O)cc(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1

InChI Key InChIKey=FXZDYVDTIVZZCX-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50388781   

TargetCasein kinase II subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388781(CHEMBL2062585)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of CK2alpha in human HCT116 cells assessed as decrease in AKT phosphorylation at S129 residue after 3 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388781(CHEMBL2062585)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388781(CHEMBL2062585)
Affinity DataIC50: <3nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388781(CHEMBL2062585)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomeodomain-interacting protein kinase 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388781(CHEMBL2062585)
Affinity DataIC50:  570nMAssay Description:Inhibition of HipK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed