BDBM50389290 CHEMBL2063756

SMILES CCNC(=O)Nc1ccc(cc1)-c1nc2CCS(=O)(=O)Cc2c(n1)N1CCOC[C@@H]1C

InChI Key InChIKey=NLFYWTSGSCFECR-AWEZNQCLSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50389290   

TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389290(CHEMBL2063756)
Affinity DataKi:  8nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50389290(CHEMBL2063756)
Affinity DataKi: >4.55E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389290(CHEMBL2063756)
Affinity DataIC50:  48nMAssay Description:Inhibition of mTOR-mediated AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389290(CHEMBL2063756)
Affinity DataIC50:  6nMAssay Description:Inhibition of mTOR-mediated ribosomal protein S6 kinase phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed