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Found 3 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase mTOR' and Ligand = 'BDBM50389290'
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389290(CHEMBL2063756)
Affinity DataKi:  8nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389290(CHEMBL2063756)
Affinity DataIC50:  6nMAssay Description:Inhibition of mTOR-mediated ribosomal protein S6 kinase phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389290(CHEMBL2063756)
Affinity DataIC50:  48nMAssay Description:Inhibition of mTOR-mediated AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed