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BDBM50420356 NC 150::PHENAZOPYRIDINE HYDROCHLORIDE

SMILES: Nc1ccc(\N=N\c2ccccc2)c(N)n1

InChI Key: InChIKey=QPFYXYFORQJZEC-FOCLMDBBSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50420356   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NAD(+) hydrolase SARM1


(Homo sapiens)
BDBM50420356
PNG
(NC 150 | PHENAZOPYRIDINE HYDROCHLORIDE)
Show SMILES Nc1ccc(\N=N\c2ccccc2)c(N)n1
Show InChI InChI=1S/C11H11N5/c12-10-7-6-9(11(13)14-10)16-15-8-4-2-1-3-5-8/h1-7H,(H4,12,13,14)/b16-15+
PDB

KEGG

UniProtKB/SwissProt

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CHEBI
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
PubMed
7.00E+4n/an/an/an/an/an/an/an/a



UMass Medical School

Curated by ChEMBL


Assay Description
Competitive inhibition of recombinant human SARM1 TIR domain (561 to 724 residues) expressed in Escherichia coli C43 (DE3) cells lysates assessed as ...


Bioorg Med Chem 28: (2020)

More data for this
Ligand-Target Pair
Snake venom metalloproteinase Bap1


(Bothrops asper)
BDBM50420356
PNG
(NC 150 | PHENAZOPYRIDINE HYDROCHLORIDE)
Show SMILES Nc1ccc(\N=N\c2ccccc2)c(N)n1
Show InChI InChI=1S/C11H11N5/c12-10-7-6-9(11(13)14-10)16-15-8-4-2-1-3-5-8/h1-7H,(H4,12,13,14)/b16-15+
PDB
MMDB

UniProtKB/SwissProt

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CHEBI
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.43E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of snake venom BaP1 using Abz-Ala-Gly-Leu-Ala-Nba as substrate incubated for 30 mins prior to substrate addition by fluorescence spectroph...


ACS Med Chem Lett 3: 540-543 (2012)


Article DOI: 10.1021/ml300068r
BindingDB Entry DOI: 10.7270/Q2542PVS
More data for this
Ligand-Target Pair
NAD(+) hydrolase SARM1


(Homo sapiens)
BDBM50420356
PNG
(NC 150 | PHENAZOPYRIDINE HYDROCHLORIDE)
Show SMILES Nc1ccc(\N=N\c2ccccc2)c(N)n1
Show InChI InChI=1S/C11H11N5/c12-10-7-6-9(11(13)14-10)16-15-8-4-2-1-3-5-8/h1-7H,(H4,12,13,14)/b16-15+
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
Purchase

CHEBI
DrugBank
MCE
KEGG
PC cid
PC sid
UniChem
PubMed
n/an/a 1.45E+5n/an/an/an/an/an/a



UMass Medical School

Curated by ChEMBL


Assay Description
Inhibition of recombinant human SARM1 TIR domain (561 to 724 residues) expressed in Escherichia coli C43 (DE3) cells lysates using ENAD as substrate ...


Bioorg Med Chem 28: (2020)

More data for this
Ligand-Target Pair