BDBM50474760 CG-100649::CG100649::Polmacoxib

SMILES CC1(C(=O)C(=C(O1)c2ccc(cc2)S(=O)(=O)N)c3cccc(c3)F)C

InChI Key InChIKey=IJWPAFMIFNSIGD-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50474760   

TargetProstaglandin G/H synthase 1(Mouse)
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50474760(CG-100649 | CG100649 | Polmacoxib)
Affinity DataIC50: 3nMAssay Description:Inhibition of COX-1 in LPS-induced mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Amorepacific R&D Center

Curated by ChEMBL
LigandPNGBDBM50474760(CG-100649 | CG100649 | Polmacoxib)
Affinity DataIC50: 8.30nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
The M.S University of Baroda

Curated by ChEMBL
LigandPNGBDBM50474760(CG-100649 | CG100649 | Polmacoxib)
Affinity DataIC50: 830nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed