BDBM50474760 CG-100649::CG100649::Polmacoxib

SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=IJWPAFMIFNSIGD-UHFFFAOYSA-N

Data  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50474760   

TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Amorepacific R&D Center

Curated by ChEMBL
LigandPNGBDBM50474760(CG-100649 | CG100649 | Polmacoxib)
Affinity DataIC50:  8.30nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
The M.S University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50474760(CG-100649 | CG100649 | Polmacoxib)
Affinity DataIC50:  3nMAssay Description:Inhibition of COX-1 in LPS-induced mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Mus musculus)
The M.S University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50474760(CG-100649 | CG100649 | Polmacoxib)
Affinity DataIC50:  830nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed