BDBM50493818 Oliceridine::TRV-130::US11124523, Comparative Compound 1::US11484525, Compound TRV-130

SMILES: COc1ccsc1CNCC[C@]2(CCOC3(C2)CCCC3)c4ccccn4

InChI Key: InChIKey=DMNOVGJWPASQDL-UHFFFAOYSA-N

Data: 6 KI  14 IC50  11 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 50493818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 1A2 (Rat)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
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Delta-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.70	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 1A2 (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
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Delta-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C19 (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.65E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium channel protein type 5 subunit alpha (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor [N127C] (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		6.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50493818 (Oliceridine | TRV-130 | US11124523, Comparative Co...) Show SMILES Show InChI	GoogleScholar	UniChem		8.32E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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