BDBM50493818 Oliceridine::TRV-130::US11124523, Comparative Compound 1::US11484525, Compound TRV-130
SMILES COc1ccsc1CNCC[C@]1(CCOC2(CCCC2)C1)c1ccccn1
InChI Key InChIKey=DMNOVGJWPASQDL-OAQYLSRUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50493818
Affinity DataKi: 6nMAssay Description:Binding affinity to human mu opioid receptor by radio-ligand binding assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Trevena
Curated by ChEMBL
Trevena
Curated by ChEMBL
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human Cav 1.2 ion channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
Affinity DataEC50: 2.80E+3nMAssay Description:Agonist activity at human delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluores...More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.90nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluores...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Trevena
Curated by ChEMBL
Trevena
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human ERG channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of human Nav 1.5 tonic ion channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human Nav 1.5 phasic ion channel expressed in HEK293 cells by whole-cell patch clamp techniqueMore data for this Ligand-Target Pair