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BDBM66223 MLS000034501::N-[4-[4-(2-furoyl)piperazino]phenyl]thiophene-2-carboxamide::N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]thiophene-2-carboxamide::N-[4-[4-(furan-2-ylcarbonyl)piperazin-1-yl]phenyl]thiophene-2-carboxamide::N-[4-[4-[2-furanyl(oxo)methyl]-1-piperazinyl]phenyl]-2-thiophenecarboxamide::SMR000014303::Thiophene-2-carboxylic acid {4-[4-(furan-2-carbonyl)-piperazin-1-yl]-phenyl}-amide::cid_645161

SMILES: O=C(Nc1ccc(cc1)N1CCN(CC1)C(=O)c1ccco1)c1cccs1

InChI Key: InChIKey=HBNQGNRHHYSKLU-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 66223   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bcl-2-like protein 11


(Homo sapiens (Human))
BDBM66223
PNG
(MLS000034501 | N-[4-[4-(2-furoyl)piperazino]phenyl...)
Show SMILES O=C(Nc1ccc(cc1)N1CCN(CC1)C(=O)c1ccco1)c1cccs1
Show InChI InChI=1S/C20H19N3O3S/c24-19(18-4-2-14-27-18)21-15-5-7-16(8-6-15)22-9-11-23(12-10-22)20(25)17-3-1-13-26-17/h1-8,13-14H,9-12H2,(H,21,24)
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KEGG

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PC cid
PC sid
UniChem
PCBioAssay
n/an/an/an/a>3.50E+5n/an/an/an/a



Broad Institute

Curated by PubChem BioAssay


Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...


PubChem Bioassay (2010)


BindingDB Entry DOI: 10.7270/Q24J0CKJ
More data for this
Ligand-Target Pair