BDBM78433 2-[4-[3-[2-(trifluoromethyl)-10-phenothiazinyl]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazino]ethanol;hydrochloride::FLUPHENAZINE::FLUPHENAZINE HYDROCHLORIDE::MLS001076508::SMR000058411::cid_3372::cid_6602611::med.21724, Compound 17

SMILES: OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1

InChI Key: InChIKey=PLDUPXSUYLZYBN-UHFFFAOYSA-N

Data: 95 KI  21 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 119 hits for monomerid = 78433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NADPH oxidase 1 (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitochondrial import inner membrane translocase subunit TIM10 (Baker's yeast)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ubiquitin-conjugating enzyme E2 N (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ubiquitin-conjugating enzyme E2 N (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bcl-2-related protein A1 (Mouse)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium channel subfamily K member 2 (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	7.3	22
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Spike glycoprotein (MERS-CoV)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Spike glycoprotein (SARS-CoV)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Orf1a protein (MERS-CoV)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.86E+3	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.14E+4	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-binding cassette sub-family C member 4 (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-binding cassette sub-family C member 2 (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Bile salt export pump (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Adenylate cyclase type 1/Adenylate cyclase type 2/Adenylate cyclase type 3/Adenylate cyclase type 4/Adenylate cyclase type 5/Adenylate cyclase type 6/Adenylate cyclase type 8/Adenylyl cyclase 7 (Rat)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (Rabbit)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Solute carrier family 22 member 1 (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Pleiotropic ABC efflux transporter of multiple drugs (Baker's yeast)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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ATP-dependent translocase ABCB1 (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-dependent translocase ABCB1 (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Potassium channel subfamily K member 2 (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium channel protein type 1/2/3 subunit alpha (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(3) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(2) dopamine receptor (Bovine)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dopamine receptor D4 (Dog)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(3) dopamine receptor (Rat)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(2) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rat)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Mouse)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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D(3) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Bovine)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Human)	BDBM78433 (2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]pro...) Show SMILES Show InChI	GoogleScholar	UniChem		1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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