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BDBM7878 2-bromo-1-(4-methylphenyl)ethan-1-one::Halomethyl Phenyl Ketone deriv. 26

SMILES: Cc1ccc(cc1)C(=O)CBr

InChI Key: InChIKey=KRVGXFREOJHJAX-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7878   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM7878
PNG
(2-bromo-1-(4-methylphenyl)ethan-1-one | Halomethyl...)
Show SMILES Cc1ccc(cc1)C(=O)CBr
Show InChI InChI=1S/C9H9BrO/c1-7-2-4-8(5-3-7)9(11)6-10/h2-5H,6H2,1H3
PDB
MMDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Instituto de Qui£?mica Medica-CSIC

Curated by ChEMBL


Assay Description
Inhibition of GSK3beta using GS1 as substrate and [gamma-32P]ATP after 20 mins by radiometric assay


J Med Chem 54: 4042-56 (2011)


Article DOI: 10.1021/jm1016279
BindingDB Entry DOI: 10.7270/Q29887C1
More data for this
Ligand-Target Pair
Glycogen Synthase Kinase-3, beta


(Oryctolagus cuniculus (rabbit))
BDBM7878
PNG
(2-bromo-1-(4-methylphenyl)ethan-1-one | Halomethyl...)
Show SMILES Cc1ccc(cc1)C(=O)CBr
Show InChI InChI=1S/C9H9BrO/c1-7-2-4-8(5-3-7)9(11)6-10/h2-5H,6H2,1H3
GoogleScholar
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/a37



Instituto de Quimica Medica (CSIC)



Assay Description
Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...


J Med Chem 46: 4631-3 (2003)


Article DOI: 10.1021/jm034108b
BindingDB Entry DOI: 10.7270/Q2DJ5CVH
More data for this
Ligand-Target Pair