BDBM84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole

SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12

InChI Key InChIKey=FTSUPYGMFAPCFZ-ZWNOBZJWSA-N

Data  113 KI  3 IC50  4 Kd  48 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 168 hits for monomerid = 84637   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  0.230nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  0.410nMAssay Description:Displacement of [3H]spiroperidol from cloned human dopamine receptor D3 in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  1.80nMAssay Description:High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  1.80nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human Dopamine receptor D4 expressed in CHO cells; high binding affinityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  1.80nMAssay Description:High binding affinity towards human dopamine receptor 4.4 expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  1.80nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D4 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine receptor D4(CANINE)
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  4.80nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  5.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  5.70nMAssay Description:Tested for binding affinity against dopamine receptor D3 expressed in Sf9 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  12.5nMAssay Description:Displacement of [3H]spiroperidol from human cloned dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  14nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  15.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  17nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]7-OH-DPAT from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  19.3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  24nMAssay Description:High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  24nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human Dopamine receptor D3 expressed in CHO cells; high binding affinityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  24nMAssay Description:High binding affinity towards human dopamine receptor 3 expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D3 in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  24nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  29.4nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  33.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  34nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  35nMAssay Description:High binding affinity towards human dopamine receptor 2 (short) expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  35nMAssay Description:High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D2S expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  37.3nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  39nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  41.7nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  43nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]YM-09151-2 from human dopamine D3 receptor expressed in CHOp cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine receptor D4(CANINE)
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  46nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  46.8nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  47nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  48nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  52nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 short receptor expressed in CHO cells; high binding affinityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  52nMAssay Description:Effective concentration for [3H]thymidine uptake in growing CHO cells stably expressing the dopamine D4.2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  53nMAssay Description:Low inhibition constant against [3H]-spiperone binding to human Dopamine receptor D4.4 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  53nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  53nMAssay Description:Low binding affinity towards human dopamine receptor 4.4 expressed in Chinese hamster ovary cells using [3H]spiperone (0.5 nM) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Dupont Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  54nMAssay Description:Compound was evaluated for its ability to displace [3H]raclopride from dopamine receptor D2 in rat striatal homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(BOVINE)
Universit£

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  59nMAssay Description:Inhibition of [3H]YM-09151-2 binding to bovine retina membrane Dopamine receptor D2, high affinity siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  63nMAssay Description:Binding affinity (high) towards human dopamine receptor 2 long against radioligand [3H]spiperone, expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  63nMAssay Description:High inhibition constant against [3H]-spiperone binding to human Dopamine receptor D2L expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  64nMAssay Description:In vitro binding affinity to displace [3H]spiperone from the cloned human dopamine receptor D2 long in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  64nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 long receptor expressed in CHO cells; high binding affinityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  124nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by PDSP Ki Database
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataKi:  140nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
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