BDBM84637 CAS_85760-74-3::CHEMBL240773::NSC_54562::QUINPIROLE::Quinpirole,(-)::US9359372, Quinpirole

SMILES CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12

InChI Key InChIKey=FTSUPYGMFAPCFZ-ZWNOBZJWSA-N

Data  113 KI  3 IC50  4 Kd  48 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 84637   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataEC50:  330nMAssay Description:Intrinsic activity against dopamine D2(long) receptor expressed in CHO cells by GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataEC50:  3.40nMAssay Description:Intrinsic activity against dopamine D3 receptor assessed as [3H]thymidine uptake in CHO cells by mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataEC50:  7.40nMAssay Description:Intrinsic activity against dopamine D2(long) receptor assessed as [3H]thymidine uptake in CHO cells by mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataEC50:  230nMAssay Description:Intrinsic activity against dopamine D2(short) receptor expressed in CHO cells by GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataEC50:  11nMAssay Description:Intrinsic activity against dopamine D4 receptor assessed as [3H]thymidine uptake in CHO cells by mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataEC50:  10nMAssay Description:Intrinsic activity against dopamine D2(short) receptor assessed as [3H]thymidine uptake in CHO cells by mitogenesis assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM84637(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)
Affinity DataEC50:  23nMAssay Description:Intrinsic activity against dopamine D4 receptor expressed in CHO cells by GTPgammaS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed