BDBM86544 CAS_192231-16-6::CHEMBL111580::NSC_6442277::SIB-1508Y
SMILES CN1CCCC1c1cncc(c1)C#C
InChI Key InChIKey=NUPUDYKEEJNZRG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 86544
TargetNeuronal acetylcholine receptor subunit alpha-4(Rattus norvegicus (Rat))
Targacept
Curated by PDSP Ki Database
Targacept
Curated by PDSP Ki Database
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Targacept
Curated by PDSP Ki Database
Targacept
Curated by PDSP Ki Database
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 1.50E+4nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 2.50E+4nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Compound was evaluated for functional potency and efficacy at rat Nicotinic acetylcholine receptor in PC12 cells (ganglionic)More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 4.10E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 4.10E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 2.30E+4nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 5.30E+4nMAssay Description:Binding affinity at NAChRs was determined by measuring the displacement of ([3H]Nic) from a preparation of rat cortical membranes.More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 5.20E+4nMAssay Description:The compound was tested on recombinant human alpha-1-beta-1-gamma-delta cell lines of human embryonic kidney for nicotinic acetylcholine receptor ago...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(RAT)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 1.01E+4nMAssay Description:The compound was tested on recombinant human alpha3-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 1.50E+4nMAssay Description:Binding affinity at NAChRs was determined by measuring the displacement of ([3H]Nic) from a preparation of rat cortical membranes.More data for this Ligand-Target Pair