Found 16 Enz. Inhib. hit(s) with Target = 'Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4' TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 562nMAssay Description:Displacement of [3H]epibatidine from alpha2beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 838nMAssay Description:Displacement of [3H]epibatidine from alpha2beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha2beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 6.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha2beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 8.00E+3nMAssay Description:Displacement of [3H]epibatidine from alpha2beta4-nAChR (unknown origin) expressed in HEK293 cells after 2 hrs by liquid scintillation counting analys...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha2beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Epibatidine from human recombinant alpha2beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-epibatidine from human alpha2beta4 nAChR transfected in HEK293 cells by scintillation counting analysisMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 9.00E+3nMAssay Description:Binding affinity at NAChRs was determined by measuring the displacement of ([3H]Nic) from a preparation of rat cortical membranes.More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:The compound was tested on recombinant human alpha2-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:The compound was tested on recombinant human alpha2-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 1.00E+4nMAssay Description:The compound was tested on recombinant human alpha2-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 286nMAssay Description:Positive allosteric modulation of human alpha2beta4 nAChR expressed in HEK cells preincubated for 15 mins followed by dihydro-beta-erythroidine hydro...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 1.50E+4nMAssay Description:The compound was tested on recombinant human alpha4-beta4 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 1.50E+4nMAssay Description:Binding affinity at NAChRs was determined by measuring the displacement of ([3H]Nic) from a preparation of rat cortical membranes.More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4(Homo sapiens (Human))
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
The Johns Hopkins University School Of Medicine
Curated by ChEMBL
Affinity DataEC50: 2.90E+4nMAssay Description:Binding affinity at NAChRs was determined by measuring the displacement of ([3H]Nic) from a preparation of rat cortical membranes.More data for this Ligand-Target Pair
