BDBM8726 5-chloro-2-(2,4-dichlorophenoxy)phenol::CHEMBL849::TCL::Triclosan::US20230414581, Compound 35

SMILES: c1cc(c(cc1Cl)O)Oc2ccc(cc2Cl)Cl

InChI Key: InChIKey=XEFQLINVKFYRCS-UHFFFAOYSA-N

Data: 30 KI  43 IC50  1 Kd

PDB links: 33 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 74 hits for monomerid = 8726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase A/A/B/B tetramer (Escherichia coli (strain K12))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.35E+4	n/a	n/a	n/a	n/a	4.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.44E+5	n/a	n/a	n/a	4.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	6.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonyl reductase [NADPH] 1 (Human)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-ACP reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Trans-2-enoyl-ACP reductase II (Streptococcus pneumoniae)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Escherichia coli (strain K12))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Trans-2-enoyl-ACP reductase II (Streptococcus pneumoniae)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Bacillus subtilis (strain 168))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Francisella tularensis subsp. tularensis (strain S...)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Endoplasmic reticulum chaperone BiP (Human)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	6.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Escherichia coli (strain K12))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	6.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Trans-2-enoyl-ACP reductase II (Streptococcus pneumoniae)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	6.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Escherichia coli (strain K12))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Escherichia coli (strain K12))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	6.8	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-ACP reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	73	n/a	n/a	n/a	n/a	7.9	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	49	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl carrier reductase ENR (Toxoplasma gondii)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-oxoacyl-[acyl-carrier-protein] synthase 3 (Escherichia coli)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Escherichia coli (strain K12))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD(+) hydrolase SARM1 (Human)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (SARS-CoV)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI (Escherichia coli (strain K12))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI (Staphylococcus aureus (strain MRSA252))	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0500	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-[acyl-carrier-protein] reductase [NADH] (Francisella tularensis)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0510	-14.0	n/a	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.0521	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Enoyl-acyl-carrier protein reductase (malaria parasite P. falciparum)	BDBM8726 (CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...) Show SMILES Show InChI	GoogleScholar	UniChem		0.109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair