Found 7 Enz. Inhib. hit(s) with Target = 'Enoyl-[acyl-carrier-protein] reductase [NADH] FabI' and Ligand = 'BDBM8726' 
Affinity DataKi: 0.00700nMAssay Description:Inhibition of wild type Escherichia coli FabI assessed as inhibition of bacterial growthMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 5nMAssay Description:Inhibition of Escherichia coli FabI using 2-dodecenoyl-CoA as substrate at pH 8More data for this Ligand-Target Pair
Affinity DataIC50: 430nMpH: 6.5 T: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMT: 2°CAssay Description:Assays were carried out in half-area, 96-well microtiter plates. Compounds were evaluated in assay mixtures containing components specific for each e...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH] FabI(Bacillus subtilis (strain 168))
University Of Illinois At Chicago
Curated by ChEMBL
University Of Illinois At Chicago
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Bacillus anthracis Enoyl ACP reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of Escherichia coli enoyl-ACP reductase FabIMore data for this Ligand-Target Pair
