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Found 165 with Last Name = 'di toro' and Initial = 'r'
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064172(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi:  0.5nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064171(1'-benzylspiro[3,4-dihydro-2H-chromene-2,4'-(hexah...)
Affinity DataKi:  0.620nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  1.05nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]-prazosin from rat submaxillary glandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50036764(1'-benzylspiro[1,2,3,4-tetrahydronaphthalene-2,4'-...)
Affinity DataKi:  1.40nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM29568(CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...)
Affinity DataKi:  2.93nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]-prazosin from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.20nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  4.80nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 using [3H]-spiperone from rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091002(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  6.10nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090990(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  6.70nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091014(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(RAT)
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064176(CHEMBL27673 | CHEMBL500996 | METHOCTRAMINE | N,N''...)
Affinity DataKi:  15nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]-NMS from rat heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091006(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50044426(1-[1-(3-Isothiocyanato-phenyl)-cyclohexyl]-piperid...)
Affinity DataKi:  16nMAssay Description:Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091011(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064173(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi:  20nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino

Curated by ChEMBL
LigandPNGBDBM50064175(1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydr...)
Affinity DataKi:  25nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090991(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091018(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090987(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091001(2-[5-Guanidino-2-(5-guanidino-2-{[2-(8-hydroxy-6,1...)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090994(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091016(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  67nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090988(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091004(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090996(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091009(2-[5-Guanidino-2-(5-guanidino-2-{[2-(8-hydroxy-6,1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091028(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  80nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090993(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091017(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091015(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090995(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  116nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091021(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091000(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  122nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50027808((Dynorphin)2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydro...)
Affinity DataKi:  124nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091005(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091008(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091012(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  149nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090997(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  156nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091029(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  176nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091027(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  192nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091003(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  204nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090989(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  216nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090992(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  238nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50001267(CHEMBL2364529)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50027808((Dynorphin)2-[2-(2-{2-[2-(2-{2-[2-Amino-3-(4-hydro...)
Affinity DataKi:  241nMAssay Description:Tested for binding affinity by [3H]diprenorphine displacement for Opioid receptor delta 1 are carried on crude membrane fractions obtained from the w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091007(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  242nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50090999(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  246nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50091010(2-(8-Hydroxy-6,11-dimethyl-1,2,5,6-tetrahydro-4H-2...)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]-U-69,593 from Opioid receptor kappa 1 in guinea pig cerebellar.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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