BDBM50064175 1-benzylspiro[hexahydropyridine-4,2'-(3',4'-dihydro-2'-sulphoxidochromene)]::CHEMBL38085
SMILES O=S1c2ccccc2CCC11CCN(Cc2ccccc2)CC1
InChI Key InChIKey=QZTBMIWQKQVGNL-UHFFFAOYSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50064175
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Compound was tested for its binding affinity towards sigma 1 receptor using [3H]-(+)-pentazocine from guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1B adrenergic receptor using [3H]-prazosin from rat liverMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
University Of Camerino
Curated by ChEMBL
University Of Camerino
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards PCP receptor using [3H]-(+)-NANM in the presence of 5 microM haloperidol from rat brainMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Dopamine receptor D2 using [3H]-spiperone from rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M2 using [3H]-NMS from rat heartMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Muscarinic acetylcholine receptor M3 using [3H]-NMS from rat submaxillary glandMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]-prazosin from rat submaxillary glandMore data for this Ligand-Target Pair