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Found 416 with Last Name = 'imran' and Initial = 's'
TargetThymidine phosphorylase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University

Curated by ChEMBL
LigandPNGBDBM50274904(CHEMBL4129617)
Affinity DataIC50:  20nMAssay Description:Inhibition of thymidine phosphorylase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Homo sapiens (Human))
Imam Abdulrahman Bin Faisal University

Curated by ChEMBL
LigandPNGBDBM20079(5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human placenta thymidine phosphorylase using [6-3H]dThd as substrate after 5 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193719(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(2-fluoro...)
Affinity DataIC50:  100nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193733(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3,4-dich...)
Affinity DataIC50:  120nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara (Uitm), Puncak Alam Campus

LigandPNGBDBM60585(2-(3'-Fluorophenyl)-7-methyl-1H-benzo[d]imidazole ...)
Affinity DataIC50:  165nMAssay Description:The 135 µL of 50 mM phosphate saline buffer pH (6.8), solution of enzyme (20 µL), and 20 µL of test sample with 70% DMSO was added to 96-well plate. ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Universiti Teknologi Mara (Uitm)

LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  180nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193734(2-(4-(di(1H-indol-3-yl)methyl)benzoyl)-N-(4(triflu...)
Affinity DataIC50:  200nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129797(CHEMBL3629072)
Affinity DataIC50:  400nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM227609((E)-5-chloro-N'-(2,4,5-trihydroxybenzylidene)-...)
Affinity DataIC50:  500nMAssay Description:β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193720(N-(2-Chlorophenyl)-2-(4-(di(1H-indol-3-yl)methyl)b...)
Affinity DataIC50:  500nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129738(CHEMBL3629545)
Affinity DataIC50:  700nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50510735(CHEMBL4567565)
Affinity DataIC50:  960nMAssay Description:Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129802(CHEMBL3629548)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara (Uitm), Puncak Alam Campus

LigandPNGBDBM178004(2-(3-((3-(trifluoromethyl)benzyl)oxy)phenyl)-4H-ch...)
Affinity DataIC50:  1.26E+3nMpH: 6.8Assay Description:The α-glucosidase inhibition assay had been carried out using baker¿s yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129798(CHEMBL3629071)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM181084(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(4-nitrophen...)
Affinity DataIC50:  1.40E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50510743(CHEMBL4462023)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129744(CHEMBL3629078)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129746(CHEMBL3629076)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464435(CHEMBL4277658)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM60592(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(4-(trifluor...)
Affinity DataIC50:  1.60E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129801(CHEMBL3629549)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM50129804(CHEMBL3629546)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of jack bean urease using urea as substrate assessed as ammonia production incubated for 15 mins by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464425(CHEMBL4284909)
Affinity DataIC50:  2.06E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM181090(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(3,4-dichlor...)
Affinity DataIC50:  2.10E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50180370(CHEMBL3813774)
Affinity DataIC50:  2.11E+3nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate assessed as formation of p-nitrophenol incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464440(CHEMBL4294256)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50092444(CHEMBL3586121)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50160569(CHEMBL3785671)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM193670(N,N'-(disulfanediylbis(2,1-phenylene))bis(2,4,...)
Affinity DataIC50:  2.20E+3nMAssay Description:β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 µL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOligo-1,6-glucosidase IMA1(Saccharomyces cerevisiae S288c (Baker's yeast))
Universiti Teknologi Mara (Uitm), Puncak Alam Campus

LigandPNGBDBM173530((E)-N'-(3,4,5-trihydroxybenzylidene)-1H-indole...)
Affinity DataIC50:  2.30E+3nMAssay Description:The 135 µL of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 µL of test sample with 70% DMSO added into the wells. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193729(2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3-fluoro...)
Affinity DataIC50:  2.30E+3nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464427(CHEMBL4292777)
Affinity DataIC50:  2.35E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM227608((E)-5-chloro-N'-(2,4,6-trihydroxybenzylidene)-...)
Affinity DataIC50:  2.40E+3nMAssay Description:β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM227625((E)-5-chloro-N'-(2-fluorobenzylidene)-1H-indol...)
Affinity DataIC50:  2.50E+3nMAssay Description:β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
Universiti Teknologi Mara (Uitm)

Curated by ChEMBL
LigandPNGBDBM181080(2-(4-(benzo[d]thiazol-2-yl)benzoyl)-N-(4-fluorophe...)
Affinity DataIC50:  2.50E+3nMpH: 6.8 T: 2°CAssay Description:To understand the binding modes of the compounds given in Table 1, all ligands were docked into the binding site of Urease enzyme. The top ranked con...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50180368(CHEMBL3814932)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate assessed as formation of p-nitrophenol incubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM50510746(CHEMBL4559353)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464428(CHEMBL4290115)
Affinity DataIC50:  2.67E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM227613((E)-4-((2-(5-chloro-1H-indole-2-carbonyl)hydrazono...)
Affinity DataIC50:  2.70E+3nMAssay Description:β-glucuronidase activity was determined in accordance to method used by Taha et al. [Taha et al., Bioorg. Med. Chem., 23:7394-7404] by measuring...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464433(CHEMBL4286367)
Affinity DataIC50:  2.75E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464434(CHEMBL4288298)
Affinity DataIC50:  2.82E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464441(CHEMBL4291709)
Affinity DataIC50:  2.87E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464431(CHEMBL4283335)
Affinity DataIC50:  2.88E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464432(CHEMBL4278776)
Affinity DataIC50:  2.88E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-glucuronidase(Homo sapiens (Human))
Universiti Teknologi Mara

LigandPNGBDBM193721(N-(2-Bromophenyl)-2-(4-(di(1H-indol-3-yl)methyl)be...)
Affinity DataIC50:  2.90E+3nMAssay Description:β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464438(CHEMBL4279414)
Affinity DataIC50:  2.93E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464439(CHEMBL4293927)
Affinity DataIC50:  2.98E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
University Of Dammam

Curated by ChEMBL
LigandPNGBDBM50464424(CHEMBL4283744)
Affinity DataIC50:  3.05E+3nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 10 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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