TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Membrane Research Group Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Membrane Research Group Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:TP_TRANSPORTER: efflux of Hoechst33342 in BCRP-expressing Sf9 cellsMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Vichem Chemie Research
Curated by ChEMBL
Vichem Chemie Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant c-MET (unknown origin) using poly-AEKY peptide as substrate after 60 mins by ADPGlo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin)More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Vichem Chemie Research
Curated by ChEMBL
Vichem Chemie Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant c-MET (unknown origin) using poly-AEKY peptide as substrate after 60 mins by ADPGlo assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Vichem Chemie Research
Curated by ChEMBL
Vichem Chemie Research
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant c-MET (unknown origin) using poly-AEKY peptide as substrate after 60 mins by ADPGlo assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of JNK1alpha1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant EGFR (unknown origin) using poly-GT peptide as substrate by Transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant INSR (unknown origin) using fluorescent dye-labelled KKSRGDYMTMQIG peptide peptide as substrate after 1 hr by IMAP assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of JNK1alpha1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of JNK1alpha1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) expressed in HEK293 cells using GST-CTDII as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant INSR (unknown origin) using fluorescent dye-labelled KKSRGDYMTMQIG peptide peptide as substrate after 1 hr by IMAP assayMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase beta-2(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of SR protein kinase 1 by compound dissolved in 100% DMSO using 5'-[gamma-33P]-triphosphateMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using MBP peptide substrate after 1 hr by FRET-based LANCE assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) expressed in HEK293 cells using GST-CTDII as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant EGFR (unknown origin) using poly-GT peptide as substrate by Transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant EGFR (unknown origin) using poly-GT peptide as substrate by Transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 129nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Affinity DataIC50: 142nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 163nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 168nMAssay Description:Inhibition of recombinant EGFR (unknown origin) using poly-GT peptide as substrate by Transcreener assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant INSR (unknown origin) using fluorescent dye-labelled KKSRGDYMTMQIG peptide peptide as substrate after 1 hr by IMAP assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assayMore data for this Ligand-Target Pair
Affinity DataIC50: 186nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Membrane Research Group Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Membrane Research Group Of The Hungarian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:TP_TRANSPORTER: efflux of Hoechst33342 in BCRP-expressing Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 212nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assayMore data for this Ligand-Target Pair
Affinity DataIC50: 246nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Affinity DataIC50: 248nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 254nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 258nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assayMore data for this Ligand-Target Pair
Affinity DataIC50: 261nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Semmelweis University
Curated by ChEMBL
Semmelweis University
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of B-Raf V600E mutant (unknown origin) using MEK1 K97M as substrate preincubated for 90 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 296nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 326nMAssay Description:FLT3(ITD) biochemical assays were performed on two different assay system platforms, using TranscreenerŽ ADP Assay FP method (BellBrook Labs, Madison...More data for this Ligand-Target Pair
Affinity DataIC50: 327nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 332nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 333nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 346nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Inhibition of CDK9/CycT1 (unknown origin) using TAMRA-Rbtide and ATP as substrate after 1 hrMore data for this Ligand-Target Pair